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An assessment of adherence to antihypertensive treatment and associated factors in patients at the Yaounde general hospital


par Roland Muntoh Chiabi
Faculty of medicine and biomedical sciences, Yaounde I University - Pharmaciae Doctor 2017
  

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CHAPTER VI: CONCLUSION AND RECOMMENDATIONS

VI.1 CONCLUSION

At the end of this study, we could say our different objectives have been attained and the following points should be retained:

Sex ratio of participants was 1.2 with male predominance of 54.90%. The mean age was 60.1 #177; 11.1 years with extremes from 33 to 88 with the 60 years and more, age group highly represented (48.60%). Most participants (88.60%) lived in urban areas and 51.43% had a non-liberal profession,the majority (66.30%) lived as couples and 40.00% had a higher level of education. Trip duration to the hospital was less than one hour for 84.60% of participants. The high socioeconomic status was greatly represented in this study (60%) and 10.9% of participants had a health insurance.

The High Normal BP group was most represented (24.60%) and 57.70% had a controlled BP. The most frequently encountered comorbidity was heart failure (24.57%). Only 18.29% of participants had a handicap.

Calcium channel blockers were the most encountered monotherapy (31.90%). The majority of participants took less than 3 different antihypertensive. The mean treatment cost was 14543 #177; 8613FCFA and most participants were in the 10000-20000FCFA monthly drug cost range. More than 90% of participants were on a once daily posology 65.70% were on monotherapy. Specialty medications were prescribed in most cases (88.60%) and 38.30% experienced side effects due to medication.

Poor adherence was observed in 32.60% of study participants.After multivariate analysis with logistic regression, 9 variables were significantly associated with poor adherence: first cycle secondary education, living singly, trip duration of one hour or more, middle socioeconomic status, uncontrolled BP status, presence of handicap, monotherapy, presence of side effects, and taking medications in the evening.

Of the 74 patients with uncontrolled BP, 86.49% had poor adherence. Patients with uncontrolled BP were associated with poor therapeutic adherence.

VI.2 RECOMMENDATIONS

At the end of this study, we formulate the following recommendations:

· To the Ministry of Public Health,

1- To reinforce information, education and communication in the whole country on non-communicable diseases especially hypertension, so that patients should know the importance of adhering to antihypertensive treatments prescribed.

2- To accelerate the implementation of the universal insurance coverage in Cameroon so that patients could easily purchase their antihypertensive drug prescribed.

· To Health Personnel,

1. Reinforce sensitization of patients with hypertension on the need to adhere to their treatments which is lifelong in order to avoid comorbidities and complications.

2. Insist on the need to prescribe generic drugs which are less expensive in order to increase access and improve treatment adherence.

3. To opt for antihypertensive drugswhich have less side effects and which are taken once daily to facilitate adherence.

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