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Etiologies, clinical presentation and hospital outcome of bacterial meningitis in children at the pediatric unit of the Yaounde -gyneco- obstetric and pediatric hospital


par Maurane Emma NDJOCK MBEA
Faculty of health sciences, University of Bamenda - MD 2019
  

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IV.1) INCIDENCE

A total number of 14868 were admitted in the general pediatric unit of the YGOPH within the studied period, among which 43 cases of bacterial meningitis were admitted with biological evidence of either leucocytes count >10 cells /mm3 or positive bacteria culture or soluble antigen, (from which bacteria were isolated in 16 cases) giving an incidence of 0.3%.

IV.2) SOCIODEMOGRAPHIC CHARACTERISTICS OF PATIENTS

Age groups

14(32.6%)

16

14

12

10

4

8

6

0

2

13(30.2%)

8(18.6%)

2(4.7%)

6(14.0%)

[1-3mths[ [3mths-1yr [ [1yr-3yrs [ [3yrs-5yrs] >5yrs

Figure 6 : Distribution of patients according to age groups

The age range of 3months - 1year had the highest percentage of 32.6 %, out of the total number of patients admitted for bacterial meningitis. The mean age of patients admitted was 22.4 months (ranging from 1 - 60 months).

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Table I: Distribution of patients according to gender

Sex Number Percentage(%)

Male 19 44.2

Female 24 55.8

Total 43 100

The female sex is noted to have the highest admission with 24 patients among the 43 cases with a sex ratio of 0.8.

IV.2.3) Type of admissions

Type of admission

26(60.5%)

30

25

20

15

10

5

0

17(39.5%)

YGOPH Referral

Figure 7: Distribution of patients according to the type of admission.

Most of the patients (60.5 %) consulted directly and 39. 5 % were referred.

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V.2.4) Distribution of patients according to year of admission

0.5 0.45 0.4 0.35 0.3 incidence per year 0.25 0.2 0.15 0.1 0.05 0 Year

0.46

0.37

0.3

0.26

0.07

2014

2015

2016

2017

2018

0.37

0.46

0.07

0.3

0.26

Figure 8: Flow chart illustrating the incidence per year at YGOPH.

From the year 2014 there was an increase in incidence of 0.37 %, with a total number of 8 cases confirmed with meningitis, to 2015 with an incidence of 0.46 % with a total number of 12 confirmed cases. Then came a sudden drop of incidence in 2016 with 0.07% with a number of 2 cases, then increased as from 2017 with 0.3% with a number of 11 cases and slightly dropped in 2018 with 0.26 % with 10 confirmed cases.

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IV.3) CLINICAL PRESENTATION OF BACTERIAL MENINGITIS Table 2: Distribution of clinical presentation according to symptoms.

Symptoms Number Percentage(%)

Neurologic

- Convulsion 26 60.5

- Cevical pain 2 4.7

Digestive

Respiratory

Behavioural

Thermal

Total 41 95.3

otl

Total 23 53.6

Total 8 18.6

Total 31 72.2

Total 10 23.3

- Loss of

consciousness

- Headache

- Diarrhea 10 23.3

- Feeding problems - Vomiting

- Irritability 10 23.3

- Respiratory distress 8 18.6

- Fever 41 95.3

2

7

6

1

4.7

2.3

16.3

14.0

Most patients presented with fever (95.3) % and convulsion (60.5) % at admission.

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Table 3: Distribution of neurological clinical presentation according to signs

Clinical signs Number Percentage(%)

Neck stiffness 9 20.9

Meningeal signs 7 16.3

Bulging fontanella 4 9.3

*Among patients with meningeal signs 7 had both Kernig and Brudzinski sign.

The clinical sign most found was neck stiffness with 20.9 % of the total patients admitted, followed by meningeal signs at 16.3 % where both Kernig and Brudzinski's signs were present in all patients who presented with meningeal signs that is 100 %.

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